Human Antibody-enabled Cardiovascular Personalized Theranosis

ABCardionostics Project

The project
"Through biotechnology and advanced imaging, we are working to identify high-risk patients earlier and offer personalized therapies."

Our Objectives

Develop novel 68Ga-labelled PET tracers and multi-marker PET/MR imaging protocols for improved atherosclerosis diagnosis.
Objective #1: Transformative Effect on Diagnosis
Develop bispecific antibodies (bsAbs), a next-generation targeted immunotherapy designed to promote plaque regression in atherosclerotic vascular disease (ASVD).
Objective #2: Transformative Effect on Therapy
1. Define plaque vulnerability by characterizing harmful and protective monocyte/macrophage (Mo/MP) subsets. 2. Identify molecular targets of human antibodies (HuAbs) and evaluate their potential as soluble biomarkers for ASVD.
Objective #3: Transformative Impact on ASVD Knowledge

8 partners from 3 European countries

consortium

Latest news